Supply agreement enables development of POINT’s next-generation Ac-225-based radioligand therapies
INDIANAPOLIS and TORONTO, Nov. 09, 2021 — POINT Biopharma Global Inc. (NASDAQ: PNT), a company accelerating the discovery, development, and global access to life changing radiopharmaceuticals, and IONETIX Corporation, a leading cyclotron technology and isotope manufacturing company, announced today a long-term supply agreement for actinium-225 (Ac-225) to support POINT’s validation, drug development, and clinical trials for Ac-225-based radiopharmaceuticals.
To create the most effective radiopharmaceutical therapies, POINT’s clinical development strategy focuses on matching the right radioisotope with the right target. POINT plans to use Ac-225 in investigational studies of PNT2001, a next-generation Prostate-Specific Membrane Antigen (PSMA) directed radioligand for non-metastatic castrate-sensitive prostate cancer (nmCSPC) and PNT2004, a Fibroblast Activation Protein-α inhibitor candidate with potential pan-cancer applications.
“Utilizing the best isotope for the job is a core philosophy at POINT,” said Dr. Joe McCann, CEO of POINT Biopharma. “Our partnership with IONETIX further strengthens our robust radioisotope supply chain and continues to advance our next-generation radiopharmaceutical platform. We are actively investing in technologies such as our CanSEEK tumor microenvironment prodrug technology to further extend the usage of potent alpha emitting medical isotopes like Ac-225, as we believe they have a key role to play in the future of radiopharmaceuticals.”
“Radiopharmaceuticals have the potential to be a life-changing and life-saving cancer treatment option to which IONETIX can make great contributions,” said Kevin Cameron, Chairman of IONETIX. “Our proprietary cyclotron technology and growing distribution network, positions us to deliver alpha radionuclide therapeutics that would otherwise not be possible. Alpha radionuclides like astatine-211 and actinium-225 hold significant promise for radiopharmaceuticals, and we are proud to help enable POINT to deliver new, potentially life-altering therapies.”
To learn more about Ac-225 as well as other medical isotopes, attend POINT’s inaugural educational webinar on Dec 6, 2021 – register online at https://hub.pointbiopharma.com/dec2021.
IONETIX is a US-based cyclotron and technology company founded in 2009. Utilizing a proprietary cyclotron technology platform, Ionetix is focused on developing innovative accelerator solutions for the production and distribution of radioisotopes used for both diagnostic and therapeutic radiopharmaceuticals. Ionetix offers turnkey services for the point-of-care supply of the diagnostic positron emission tomography (PET) radiopharmaceutical N-13 Ammonia. Ionetix is now expanding its services to include the supply of therapeutic alpha isotopes used in radiopharmaceuticals being developed to treat various cancers. Located in Lansing, Michigan, Ionetix is establishing the first dedicated alpha isotope manufacturing and distribution facility to produce alpha isotopes Actinium-225 (Ac-225) and Astatine-211 (At-211). https://www.ionetix.com/
About POINT Biopharma
POINT Biopharma Global Inc. is a globally focused radiopharmaceutical company building a platform for the clinical development and commercialization of radioligands that fight cancer. POINT Biopharma Global Inc. is combining a portfolio of best-in-class radiopharmaceutical assets, a seasoned management team, expertise in radioisotopes such as Actinium-225 (Ac-225) and Lutetium-177 (Lu-177), and industry-leading manufacturing capabilities and supply chain to revolutionize theragnostic drug development and radioligand commercialization. Learn more about POINT Biopharma Global Inc. at https://www.pointbiopharma.com. Information about POINT Biopharma Global Inc.’s Phase 3 SPLASH trial for metastatic castrate resistant prostate cancer (mCRPC) patients can be found at https://www.splashtrial.com.
Forward Looking Statements
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